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| Home > Weekly Question | next question: 7/9/2007 |
Question of the Week:
Captopril, and ACE inhibitor, is beneficial to children with congestive heart failure secondary to large ventricular septal defect. Which of the following statements is correct regarding the mechanism through which captopril improves congestive heart failure in children with congestive heart failure secondary to left to right shunt lesions?
| A. | Captopril reduces systemic vascular resistance, thus reducing the afterload encountered by the left ventricle. |
| B. | Captopril increases the volume of left to right shunt at the ventricular septal defect by reducing systemic vascular resistance more than pulmonary vascular resistance. |
| C. | Captopril elevates pulmonary vascular resistance, thus reduces left to right shunting at the ventricular septal defect. |
| D. | Captopril inhibits myocardial cAMP phosphodiesterase, which improves myocardial function. |
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